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21 day use hotels sorted by top rated from 22 USD in Chicago, United States

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City views at Viceroy Chicago. City views at Viceroy Chicago.
King bed at Viceroy Chicago. King bed at Viceroy Chicago.
Rooftop pool at Viceroy Chicago. Rooftop pool at Viceroy Chicago.
Hotel entrance at Viceroy Chicago. Hotel entrance at Viceroy Chicago.
Hotel bar at Viceroy Chicago. Hotel bar at Viceroy Chicago.
Romantic king room at Viceroy Chicago. Romantic king room at Viceroy Chicago.
Outdoor pool at Viceroy Chicago. Outdoor pool at Viceroy Chicago.
Fitness center at Viceroy Chicago. Fitness center at Viceroy Chicago.
Coworking lounge at Viceroy Chicago. Coworking lounge at Viceroy Chicago.
Meeting room at Viceroy Chicago. Meeting room at Viceroy Chicago.
Pet friendly rooms at Viceroy Chicago. Pet friendly rooms at Viceroy Chicago.
In-room Work Desk
Pool Access
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Viceroy Chicago

4.6/5
Chicago, IL
24
views today
New
Day use room
Transit
Cozy
Pay Later at property
Free cancellation
From 155 USD 217 USD + 3.78 coins
8AM - 3PM 10AM - 6PM
Refreshing indoor pool at Hyatt Place Chicago/Hoffman Estates. Refreshing indoor pool at Hyatt Place Chicago/Hoffman Estates.
Day use room with natural light at Hyatt Place Chicago/Hoffman Estates. Day use room with natural light at Hyatt Place Chicago/Hoffman Estates.
Day use room with living area at Hyatt Place Chicago/Hoffman Estates. Day use room with living area at Hyatt Place Chicago/Hoffman Estates.
Fitness center available at Hyatt Place Chicago/Hoffman Estates. Fitness center available at Hyatt Place Chicago/Hoffman Estates.
Meeting room at Hyatt Place Chicago/Hoffman Estates. Meeting room at Hyatt Place Chicago/Hoffman Estates.
In-room work desk at Hyatt Place Chicago/Hoffman Estates. In-room work desk at Hyatt Place Chicago/Hoffman Estates.
Day use room at Hyatt Place Chicago/Hoffman Estates. Day use room at Hyatt Place Chicago/Hoffman Estates.
Guest bathroom with shower and tub at Hyatt Place Chicago/Hoffman Estates. Guest bathroom with shower and tub at Hyatt Place Chicago/Hoffman Estates.
Business center available at Hyatt Place Chicago/Hoffman Estates. Business center available at Hyatt Place Chicago/Hoffman Estates.
Dining area perfect for coworking at Hyatt Place Chicago/Hoffman Estates. Dining area perfect for coworking at Hyatt Place Chicago/Hoffman Estates.
Lobby and coworking lounge at Hyatt Place Chicago/Hoffman Estates. Lobby and coworking lounge at Hyatt Place Chicago/Hoffman Estates.
Parking area at Hyatt Place Chicago/Hoffman Estates. Parking area at Hyatt Place Chicago/Hoffman Estates.
In-room Work Desk
Pool Access
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Hyatt Place Chicago/Hoffman Estates

4.4/5
Hoffman Estates, IL
1159
views today
Coins boost
Day use room
Transit
Cozy
Pay Later at property
Free cancellation
From 69 USD 97 USD 1.68 coins Boost +1.03
8AM - 12PM 9AM - 330PM 10AM - 6PM
Royal Sonesta Chicago River North’s patio is furnished with chairs, loungers, and sofas, and offers city views. Royal Sonesta Chicago River North’s patio is furnished with chairs, loungers, and sofas, and offers city views.
Royal Sonesta Chicago River North’s indoor pool features floor-to-ceiling windows and tables and chairs, and loungers, by the side. Royal Sonesta Chicago River North’s indoor pool features floor-to-ceiling windows and tables and chairs, and loungers, by the side.
Royal Sonesta Chicago River North double bed guest room, furnished with bedside lamps, coffee table, and an armchair. Royal Sonesta Chicago River North double bed guest room, furnished with bedside lamps, coffee table, and an armchair.
The hotel fitness center is equipped with a range of exercise machines, and large windows with city views. The hotel fitness center is equipped with a range of exercise machines, and large windows with city views.
The lounge in Royal Sonesta Chicago River North has comfy chairs and numerous sofas, coffee tables, and large windows creating plenty of natural light. The lounge in Royal Sonesta Chicago River North has comfy chairs and numerous sofas, coffee tables, and large windows creating plenty of natural light.
Royal Sonesta Chicago River North double bed guest room featuring chairs, coffee table, window, and a sofa. Royal Sonesta Chicago River North double bed guest room featuring chairs, coffee table, window, and a sofa.
Double bed guest room in Royal Sonesta Chicago River North, including coffee table, two chairs, and a large window. Double bed guest room in Royal Sonesta Chicago River North, including coffee table, two chairs, and a large window.
Hotel meeting room, with long wooden table, eight swivel chairs, and floor-to-ceiling windows. Hotel meeting room, with long wooden table, eight swivel chairs, and floor-to-ceiling windows.
In-room Work Desk
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Royal Sonesta Chicago River North

4.4/5
Chicago, IL
1302
views today
Coins boost
Day use room
Transit
Work friendly
Cozy
Luxury
Pay Later at property
Free cancellation
From 135 USD 189 USD 3.29 coins Boost +2.02
10AM - 4PM
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King size bed, sofa and desk in a hotel room at the Drake. King size bed, sofa and desk in a hotel room at the Drake.
Spacious family room with king size bed and working station at the Drake. Spacious family room with king size bed and working station at the Drake.
Comfortable working station in a king hotel room at the Drake. Comfortable working station in a king hotel room at the Drake.
The Drake The Drake
Fully equipped fitness center at the Drake. Fully equipped fitness center at the Drake.
Elegant event room with big windows, chairs and tables at the Drake. Elegant event room with big windows, chairs and tables at the Drake.
Workspace in a lobby hotel at the Drake. Workspace in a lobby hotel at the Drake.
In-room Work Desk
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The Drake

4.4/5
Chicago, IL
292
views today
Room selection
Day use room
Transit
Work friendly
From 97 USD 136 USD + 2.36 coins
8AM - 4PM
Spacious, king bed with natural light at Hampton Inn Chicago North-Loyola Station. Spacious, king bed with natural light at Hampton Inn Chicago North-Loyola Station.
King bed with work desk and natural light at Hampton Inn Chicago North-Loyola Station. King bed with work desk and natural light at Hampton Inn Chicago North-Loyola Station.
Well-equipped fitness center at Hampton Inn Chicago North-Loyola Station. Well-equipped fitness center at Hampton Inn Chicago North-Loyola Station.
Spacious, professional meeting room at Hampton Inn Chicago North-Loyola Station. Spacious, professional meeting room at Hampton Inn Chicago North-Loyola Station.
Beautiful rooftop terrace at Hampton Inn Chicago North-Loyola Station. Beautiful rooftop terrace at Hampton Inn Chicago North-Loyola Station.
Hampton Inn Chicago North/Loyola Station Hampton Inn Chicago North/Loyola Station
In-room Work Desk
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Hampton Inn Chicago North/Loyola Station

4.4/5
Chicago, IL
227
views today
Room selection
Day use room
Work friendly
From 105 USD 147 USD + 2.55 coins
9AM - 5PM
Day use room with a view of the river at Hyatt Regency Chicago. Day use room with a view of the river at Hyatt Regency Chicago.
Day use room with sofa at Hyatt Regency Chicago. Day use room with sofa at Hyatt Regency Chicago.
Hotel bar with natural light at Hyatt Regency Chicago. Hotel bar with natural light at Hyatt Regency Chicago.
Fitness center at Hyatt Regency Chicago. Fitness center at Hyatt Regency Chicago.
Meeting room at Hyatt Regency Chicago. Meeting room at Hyatt Regency Chicago.
Day use room with sofa at Hyatt Regency Chicago. Day use room with sofa at Hyatt Regency Chicago.
Guest bathroom with shower and tub at Hyatt Regency Chicago. Guest bathroom with shower and tub at Hyatt Regency Chicago.
One of the 4 restaurants at Hyatt Regency Chicago. One of the 4 restaurants at Hyatt Regency Chicago.
One of the 4 restaurants at Hyatt Regency Chicago. One of the 4 restaurants at Hyatt Regency Chicago.
Self check-in and check-out kiosk available at Hyatt Regency Chicago. Self check-in and check-out kiosk available at Hyatt Regency Chicago.
In-room Work Desk
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Hyatt Regency Chicago

4.4/5
Chicago, IL
833
views today
Coins boost
Day use room
Workspace
Work friendly
Pay Later at property
Free cancellation
From 139 USD 195 USD 3.39 coins Boost +2.07
8AM - 6PM
Day use room at Hampton Inn Chicago O`Hare. Day use room at Hampton Inn Chicago O`Hare.
Dining area perfect for coworking at Hampton Inn Chicago O`Hare. Dining area perfect for coworking at Hampton Inn Chicago O`Hare.
Refreshing indoor pool at Hampton Inn Chicago O`Hare. Refreshing indoor pool at Hampton Inn Chicago O`Hare.
Fitness center available at Hampton Inn Chicago O`Hare. Fitness center available at Hampton Inn Chicago O`Hare.
Meeting room available at Hampton Inn Chicago O`Hare. Meeting room available at Hampton Inn Chicago O`Hare.
Business center available at Hampton Inn Chicago O`Hare. Business center available at Hampton Inn Chicago O`Hare.
Guest bathroom with shower at Hampton Inn Chicago O`Hare. Guest bathroom with shower at Hampton Inn Chicago O`Hare.
Spacious day use room with sofa and work desk at Hampton Inn Chicago O`Hare. Spacious day use room with sofa and work desk at Hampton Inn Chicago O`Hare.
Hotel exterior at Hampton Inn Chicago O`Hare. Hotel exterior at Hampton Inn Chicago O`Hare.
In-room Work Desk
Pool Access
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Hampton Inn Chicago O`Hare

4.4/5
Chicago, IL
328
views today
Day use room
Work friendly
From 119 USD 167 USD + 2.9 coins
9AM - 2PM
Day use room with living area at Hyatt Place Chicago, Lombard / Oak Brook. Day use room with living area at Hyatt Place Chicago, Lombard / Oak Brook.
Refreshing indoor pool at Hyatt Place Chicago, Lombard / Oak Brook. Refreshing indoor pool at Hyatt Place Chicago, Lombard / Oak Brook.
Fitness facility at Hyatt Place Chicago, Lombard / Oak Brook. Fitness facility at Hyatt Place Chicago, Lombard / Oak Brook.
Hotel bar perfect for coworking at Hyatt Place Chicago, Lombard / Oak Brook. Hotel bar perfect for coworking at Hyatt Place Chicago, Lombard / Oak Brook.
Parking area at Hyatt Place Chicago, Lombard / Oak Brook. Parking area at Hyatt Place Chicago, Lombard / Oak Brook.
Day use room at Hyatt Place Chicago, Lombard / Oak Brook. Day use room at Hyatt Place Chicago, Lombard / Oak Brook.
Guest bathroom with shower at Hyatt Place Chicago, Lombard / Oak Brook. Guest bathroom with shower at Hyatt Place Chicago, Lombard / Oak Brook.
Pool Access
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Hyatt Place Chicago, Lombard / Oak Brook

4.4/5
Lombard, IL
1085
views today
Coins boost
Day use room
Transit
Work friendly
Cozy
Pay Later at property
Free cancellation
From 199 USD 279 USD 4.86 coins Boost +2.96
8AM - 5PM
Hilton Chicago Hilton Chicago
Hilton Chicago Hilton Chicago
Hilton Chicago Hilton Chicago
Hilton Chicago Hilton Chicago
Hilton Chicago Hilton Chicago
In-room Work Desk
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Hilton Chicago

4.3/5
Chicago, IL
405
views today
Room selection
Day use room
Work friendly
From 575 USD 804 USD + 14.02 coins
9AM - 5PM
Day use room with TV at Homewood Suites By Hilton Chicago-Downtown. Day use room with TV at Homewood Suites By Hilton Chicago-Downtown.
Large indoor pool at Homewood Suites By Hilton Chicago-Downtown. Large indoor pool at Homewood Suites By Hilton Chicago-Downtown.
King room with private bathroom at Homewood Suites By Hilton Chicago-Downtown. King room with private bathroom at Homewood Suites By Hilton Chicago-Downtown.
In-room kitchen at Homewood Suites By Hilton Chicago-Downtown. In-room kitchen at Homewood Suites By Hilton Chicago-Downtown.
Day room with TV at Homewood Suites By Hilton Chicago-Downtown. Day room with TV at Homewood Suites By Hilton Chicago-Downtown.
Private bathroom at Homewood Suites By Hilton Chicago-Downtown. Private bathroom at Homewood Suites By Hilton Chicago-Downtown.
Gym available at Homewood Suites By Hilton Chicago-Downtown. Gym available at Homewood Suites By Hilton Chicago-Downtown.
Lounge and coworking space at Homewood Suites By Hilton Chicago-Downtown. Lounge and coworking space at Homewood Suites By Hilton Chicago-Downtown.
Professional meeting room at Homewood Suites By Hilton Chicago-Downtown. Professional meeting room at Homewood Suites By Hilton Chicago-Downtown.
Breakfast available at Homewood Suites By Hilton Chicago-Downtown. Breakfast available at Homewood Suites By Hilton Chicago-Downtown.
Professional conference room at Homewood Suites By Hilton Chicago-Downtown. Professional conference room at Homewood Suites By Hilton Chicago-Downtown.
Lounge and lobby at Homewood Suites By Hilton Chicago-Downtown. Lounge and lobby at Homewood Suites By Hilton Chicago-Downtown.
Dining and coworking space at Homewood Suites By Hilton Chicago-Downtown. Dining and coworking space at Homewood Suites By Hilton Chicago-Downtown.
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Homewood Suites By Hilton Chicago-Downtown

4.3/5
Chicago, IL
323
views today
Room selection
Day use room
Transit
Cozy
From 71 USD 99 USD + 1.73 coins
9AM - 7PM
beautiful king suite with TV and work desk with lots of natural light at Hilton Rosemont/Chicago O'Hare. beautiful king suite with TV and work desk with lots of natural light at Hilton Rosemont/Chicago O'Hare.
lovely indoor pool with surround seating area at Hilton Rosemont/Chicago O'Hare. lovely indoor pool with surround seating area at Hilton Rosemont/Chicago O'Hare.
spacious king room with TV and work area ideal for working remotely at Hilton Rosemont/Chicago O'Hare. spacious king room with TV and work area ideal for working remotely at Hilton Rosemont/Chicago O'Hare.
well equipped fitness center at Hilton Rosemont/Chicago O'Hare. well equipped fitness center at Hilton Rosemont/Chicago O'Hare.
dedicated business center with work desk, PC, internet, and printers at Hilton Rosemont/Chicago O'Hare. dedicated business center with work desk, PC, internet, and printers at Hilton Rosemont/Chicago O'Hare.
Hilton Rosemont/Chicago O'Hare Hilton Rosemont/Chicago O'Hare
professional meeting room at Hilton Rosemont/Chicago O'Hare. professional meeting room at Hilton Rosemont/Chicago O'Hare.
In-room Work Desk
Pool Access
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Hilton Rosemont/Chicago O'Hare

4.2/5
Chicago, IL
1050
views today
Coins boost
Room selection
Day use room
Transit
Work friendly
From 103 USD 145 USD 2.52 coins Boost +1.54
9AM - 5PM
lovely delux king room at Palmer House a Hilton Hotel. lovely delux king room at Palmer House a Hilton Hotel.
spacious king suite with work desk and lounger at Palmer House a Hilton Hotel. spacious king suite with work desk and lounger at Palmer House a Hilton Hotel.
well equipped fitness center with treadmills and weights at Palmer House a Hilton Hotel. well equipped fitness center with treadmills and weights at Palmer House a Hilton Hotel.
professional meeting room for all business meetings at Palmer House a Hilton Hotel. professional meeting room for all business meetings at Palmer House a Hilton Hotel.
cosy lounge area ideal as a coworking space at Palmer House a Hilton Hotel. cosy lounge area ideal as a coworking space at Palmer House a Hilton Hotel.
In-room Work Desk
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Palmer House A Hilton Hotel

4.2/5
Chicago, IL
1198
views today
Coins boost
Room selection
Day use room
Work friendly
From 142 USD 199 USD 3.47 coins Boost +2.12
9AM - 5PM
Stunning city landmarks nearby at Royal Sonesta Chicago Downtown. Stunning city landmarks nearby at Royal Sonesta Chicago Downtown.
Day use room with natural light at Royal Sonesta Chicago Downtown. Day use room with natural light at Royal Sonesta Chicago Downtown.
The lobby lounge of Royal Sonesta Chicago Downtown is furnished with comfortable seats and coffee tables close to a fireplace, with art on the walls. The lobby lounge of Royal Sonesta Chicago Downtown is furnished with comfortable seats and coffee tables close to a fireplace, with art on the walls.
The hotel terrace offers elevated city views and comfy seating beside coffee tables, plus a fire pit. The hotel terrace offers elevated city views and comfy seating beside coffee tables, plus a fire pit.
Royal Sonesta Chicago Downtown double bed guest room, including mirror and art on the wall, armchair, and views of the city. Royal Sonesta Chicago Downtown double bed guest room, including mirror and art on the wall, armchair, and views of the city.
Guest bathroom with shower at Royal Sonesta Chicago Downtown. Guest bathroom with shower at Royal Sonesta Chicago Downtown.
Spacious day use room with lounge at Royal Sonesta Chicago Downtown. Spacious day use room with lounge at Royal Sonesta Chicago Downtown.
Romantic king room at Royal Sonesta Chicago Downtown. Romantic king room at Royal Sonesta Chicago Downtown.
King room with kitchen at Royal Sonesta Chicago Downtown. King room with kitchen at Royal Sonesta Chicago Downtown.
Double bed guest room in Royal Sonesta Chicago Downtown, featuring city views, an armchair, and a large, wall-mounted television. Double bed guest room in Royal Sonesta Chicago Downtown, featuring city views, an armchair, and a large, wall-mounted television.
Royal Sonesta Chicago Downtown guest room lounge, with large sofa, chair, and coffee table, plus a wall-mounted TV. Royal Sonesta Chicago Downtown guest room lounge, with large sofa, chair, and coffee table, plus a wall-mounted TV.
Royal Sonesta Chicago Downtown’s fitness center is equipped with free weights and assorted exercise machines, and has a mirrored wall and city views. Royal Sonesta Chicago Downtown’s fitness center is equipped with free weights and assorted exercise machines, and has a mirrored wall and city views.
Outside restaurant at Royal Sonesta Chicago Downtown. Outside restaurant at Royal Sonesta Chicago Downtown.
Royal Sonesta Chicago Downtown meeting room, including long table and swivel chairs, with views of the urban landscape. Royal Sonesta Chicago Downtown meeting room, including long table and swivel chairs, with views of the urban landscape.
Meeting space at Royal Sonesta Chicago Downtown. Meeting space at Royal Sonesta Chicago Downtown.
Game room at Royal Sonesta Chicago Downtown. Game room at Royal Sonesta Chicago Downtown.
Meeting space with city view at Royal Sonesta Chicago Downtown. Meeting space with city view at Royal Sonesta Chicago Downtown.
Convenience store and snacks available at Royal Sonesta Chicago Downtown. Convenience store and snacks available at Royal Sonesta Chicago Downtown.
The hotel’s restaurant offers on-site dining, a mix of bar stools alongside small tables and chairs, and multiple widescreen televisions. The hotel’s restaurant offers on-site dining, a mix of bar stools alongside small tables and chairs, and multiple widescreen televisions.
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Royal Sonesta Chicago Downtown

4.2/5
Chicago, IL
1340
views today
Coins boost
Day use room
Transit
Cozy
Pay Later at property
Free cancellation
From 145 USD 203 USD 3.54 coins Boost +2.16
10AM - 6PM
The Allegro Royal Sonesta Hotel Chicago Loop double bed guest room, with art on the wall and a workspace desk and chair. The Allegro Royal Sonesta Hotel Chicago Loop double bed guest room, with art on the wall and a workspace desk and chair.
The Allegro Royal Sonesta Hotel Chicago Loop’s lobby lounge includes a table, comfortable seating, and a fireplace. The Allegro Royal Sonesta Hotel Chicago Loop’s lobby lounge includes a table, comfortable seating, and a fireplace.
The fitness center in The Allegro Royal Sonesta Hotel Chicago Loop has assorted types of exercise machine and motivational artwork on the wall. The fitness center in The Allegro Royal Sonesta Hotel Chicago Loop has assorted types of exercise machine and motivational artwork on the wall.
The Allegro Royal Sonesta Hotel Chicago Loop meeting room, with long wooden table, art on one wall and a large TV on the other. The Allegro Royal Sonesta Hotel Chicago Loop meeting room, with long wooden table, art on one wall and a large TV on the other.
Lounge within a guest room of The Allegro Royal Sonesta Hotel Chicago Loop, including sofa, armchairs, coffee tables, and a window. Lounge within a guest room of The Allegro Royal Sonesta Hotel Chicago Loop, including sofa, armchairs, coffee tables, and a window.
The Allegro Royal Sonesta Hotel Chicago Loop double bed guest room, furnished with workspace desk and chair, window, and an armchair and coffee table. The Allegro Royal Sonesta Hotel Chicago Loop double bed guest room, furnished with workspace desk and chair, window, and an armchair and coffee table.
Guest bathroom in The Allegro Royal Sonesta Hotel Chicago Loop, featuring bath and shower, and a lavatory. Guest bathroom in The Allegro Royal Sonesta Hotel Chicago Loop, featuring bath and shower, and a lavatory.
The hotel’s restaurant offers both table and booth seating, with a mix of white seats and dark wood tables, plus a bar. The hotel’s restaurant offers both table and booth seating, with a mix of white seats and dark wood tables, plus a bar.
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The Allegro Royal Sonesta Hotel Chicago Loop

4.2/5
Chicago, IL
1463
views today
Coins boost
Day use room
Transit
Work friendly
Cozy
Pay Later at property
Free cancellation
From 119 USD 167 USD 2.9 coins Boost +1.78
10AM - 5PM
King bedroom with desk and sofa at La Quinta Inn & Suites By Wyndham Chicago Downtown. King bedroom with desk and sofa at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Hotel suite with fireplace and TV screen at La Quinta Inn & Suites By Wyndham Chicago Downtown. Hotel suite with fireplace and TV screen at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Fitness center at La Quinta Inn & Suites By Wyndham Chicago Downtown. Fitness center at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Lobby workspace at La Quinta Inn & Suites By Wyndham Chicago Downtown. Lobby workspace at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Business center with computers and printer at La Quinta Inn & Suites By Wyndham Chicago Downtown. Business center with computers and printer at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Guest bathroom at La Quinta Inn & Suites By Wyndham Chicago Downtown. Guest bathroom at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Workstation in a hotel room at La Quinta Inn & Suites By Wyndham Chicago Downtown. Workstation in a hotel room at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Dining area suitable for co-working at La Quinta Inn & Suites By Wyndham Chicago Downtown. Dining area suitable for co-working at La Quinta Inn & Suites By Wyndham Chicago Downtown.
Meeting room with round tables at La Quinta Inn & Suites By Wyndham Chicago Downtown. Meeting room with round tables at La Quinta Inn & Suites By Wyndham Chicago Downtown.
In-room Work Desk
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La Quinta Inn & Suites By Wyndham Chicago Downtown

4.2/5
Chicago, IL
382
views today
Day use room
Workspace
Transit
Work friendly
Budget
Pay Later at property
Free cancellation
From 89 USD 125 USD + 2.17 coins
9AM - 5PM
More hotels
Exploring day use hotels in Chicago and wondering what to do during your downtime? Fear not, friend—we’re here to help.
 
Quintessential Things to Complement Your Chicago Day Hotel Experience
 
Seven Chicago Facts We Love
 
  1. The Chicago River flows in reverse!
  2. Debuted the world’s’ first ferris wheel at World’s Columbian Exposition in 1893
  3. ...and it was 68 feet taller than Navy Pier’s current wheel.
  4. Four states are visible from the top of the Willis Tower (MI, WI, IN, IL)
  5. Home to world’s first skyscraper, 1885’s 10-story Home Insurance Building
  6. First gay rights group was created in Chicago in 1924.
  7. Chicago opened the first U.S. blood bank in 1937.